Formalin-fixed, paraffin-embedded Human Pancreas stained with CFTR Rabbit Recombinant Monoclonal Antibody (CFTR/1775R).

CFTR Antibody (aa 258-385, clone CFTR/1775R)

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Antibody:	Rabbit Recombinant Monoclonal
Applications:	Immunohistochemistry, Paraffin
Reactivity:	Human
Format:	Liquid

$379.00each

Catalog Number: LS-C751090-20

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Description: CFTR antibody LS-C751090 is an unconjugated rabbit recombinant monoclonal antibody to human CFTR (aa 258-385). Validated for IHC.
Application: IHC-P
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: ABC35 | ABCC7 | CF | DJ760C5.1 | MRP7 | CFTR | CFTR/MRP | TNR-CFTR
Recommended Dilution: IHC-P: 1 - 2 µg/ml
UniProt Number: P13569
NCBI GenBank: NM_000492 | NP_000483.3
SwissProt: P13569

Target: Human CFTR
Antigen Species: Human
Epitope: Recognizes a protein of 165-170 kDa , identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
Gene Name: CFTR

Immunogen: Recombinant fragment (around aa 258-385) of human CFTR protein. Antigen Molecular Weight: 165-170 kDa
Immunogen Type: Recombinant Protein Fragment