CFB / Complement Factor B Antibody (N-Terminus, clone 014III-33.2.4.3)
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| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$540.00each
Catalog Number: LS-C44996-0.1
Catalog Number: LS-C44996
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- Description
- Complement Factor B antibody LS-C44996 is an unconjugated mouse monoclonal antibody to human Complement Factor B (CFB) (N-Terminus). Validated for ELISA, Flow, IHC and WB.
- Application
- ELISA, FC, IHC, IHC-F, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- AHUS4 | B-factor, properdin | C3/C5 convertase | CFAB | C3 proaccelerator | C3 proactivator | Complement factor B | Complement protein Factor B | Glycine-rich beta-glycoprotein | GBG | Factor B | FB | Glycine-rich beta glycoprotein | PBF2 | BF | BFD | CFB | FBI12 | H2-Bf | Properdin factor B
- UniProt Number
- P00751
- NCBI GenBank
- NM_001710 | NP_001701.2
- SwissProt
- P00751
Target
- Target
- Human CFB / Complement Factor B
- Antigen Species
- Human
- Epitope
- Recognizes the 30kD Ba fragment of 90kD human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kD Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes. Binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.
- Gene Name
- CFB
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 014III-33.2.4.3
- Isotype
- IgG1
Immunogen
- Immunogen
- Purified human complement factor b.
- Immunogen Type
- Native Protein (Purified from Natural Source)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- BBS, 0.1% Sodium Azide
- Concentration
- 1 mg/mL
- Volume
- 0.1 Milliliter
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- bbs