Formalin-fixed, paraffin-embedded human Pancreas stained with CELA3B Rabbit Recombinant Monoclonal Antibody (CELA3B/2809R).
CELA3B / ELA3B Antibody (aa 82-238, clone CELA3B/2809R, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751140-100
Catalog Number: LS-C751140
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- Description
- ELA3B antibody LS-C751140 is an unconjugated rabbit recombinant monoclonal antibody to human ELA3B (CELA3B) (aa 82-238). Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- CBPP | CELA3B | Elastase 1 | ELA3B | Elastase IIIB | Elastase-3B | EL-1 | Fecal elastase 1 | Pancreatic elastase IIIb | Pancreatic elastase 1 | Pancreatic endopeptidase E | Protease E | Elastase 3B, pancreatic | Proteinase E
- Recommended Dilution: IHC-P
- 1 - 2 µg/ml
- UniProt Number
- P08861
- NCBI GenBank
- NM_007352 | NP_031378.1
- SwissProt
- P08861
Target
- Target
- Human CELA3B / ELA3B
- Antigen Species
- Human
- Epitope
- This MAb recognizes a protein of ~30 kDa , identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function.
- Gene Name
- CELA3B
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- CELA3B/2809R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant human CELA3B protein fragment (around aa 82-238). Antigen Molecular Weight: ~17 kDa
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS