Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with CDX2 Rabbit Recombinant Monoclonal Antibody (CDX2/2951R).

CDX2 Antibody (aa150-249, clone CDX2/2951R)

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Antibody:	Rabbit Recombinant Monoclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:	Human
Format:	Liquid

$379.00each

Catalog Number: LS-C751081-20

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Description: CDX2 antibody LS-C751081 is an unconjugated rabbit recombinant monoclonal antibody to human CDX2 (aa150-249). Validated for ELISA and IHC.
Application: ELISA, IHC, IHC-P
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: Caudal-type homeobox protein 2 | CDX2 | CDX3 | Homeobox protein CDX-2 | Caudal type homeobox 2 | CDX-3
Recommended Dilution: ELISA: 2 - 4 ug/ml
Recommended Dilution: IHC-P: 1 - 2 µg/ml
UniProt Number: Q99626
NCBI GenBank: NM_001265 | NP_001256.3
SwissProt: Q99626

Target: Human CDX2
Antigen Species: Human
Epitope: The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
Gene Name: CDX2

Immunogen: Recombinant fragment (around aa150-249) of human CDX2 protein. Antigen Molecular Weight: 40 kDa
Immunogen Type: Recombinant Protein Fragment