LSBio
CD86 Antibody (clone rC86/1146)

Formalin-fixed, paraffin-embedded human Colon stained with CD86 Mouse Recombinant Monoclonal Antibody (rC86/1146).

CD86 Antibody (clone rC86/1146)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Recombinant Monoclonal
Applications:Flow Cytometry, Immunofluorescence, Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
See all Human CD86 antibodies →
$379.00each
Catalog Number: LS-C751450-20

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Overview

Description
CD86 antibody LS-C751450 is an unconjugated mouse recombinant monoclonal antibody to human CD86. Validated for Flow, IF and IHC.
Application
FC, IF, IHC-P
Reactivity
Hu
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
Activation B7-2 antigen | B7-2 | B7.2 | B70 | CD86 molecule | CD86 | CTLA-4 counter-receptor B7.2 | CD86 antigen | FUN-1 | LAB72 | BU63 | CD28LG2 | Ctla-4 counter-receptors b7.2
Recommended Dilution: FC
1 - 2 µg/10E6 cells
Recommended Dilution: IF/ICC
1 - 2 µg/ml
Recommended Dilution: IHC-P
2 - 4 µg/ml
UniProt Number
P42081
SwissProt
P42081

Target

Target
Human CD86
Antigen Species
Hu
Epitope
Recognizes a protein of 70 kDa , which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
Gene Name
CD86

Antibody

Host Species
Ms
Clonality
Recombinant Monoclonal
Clone
rC86/1146
Isotype
IgG1
Light Chain
κ
Origin Species
Hu

Immunogen

Immunogen
Recombinant full-length human CD86 protein. Antigen Molecular Weight: 70 kDa
Immunogen Type
Recom

Format

Conjugate/Label
Unconj
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Preservative
Yes
Purification Method
Prot A/G

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.