CD86 Antibody (clone PO3, RPE)

Name: CD86 Antibody (clone PO3, RPE)
Brand: LSBio
SKU: LS-C44891-100
Price: 413 USD
Availability: InStock

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$413.00each

Catalog Number: LS-C44891-100

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Description: CD86 antibody LS-C44891 is an RPE-conjugated rat monoclonal antibody to mouse CD86. Validated for Flow.
Application: FC
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: Activation B7-2 antigen | B7-2 | B7.2 | B70 | CD86 molecule | CD86 | CTLA-4 counter-receptor B7.2 | CD86 antigen | FUN-1 | LAB72 | BU63 | CD28LG2 | Ctla-4 counter-receptors b7.2
Recommended Dilution: FC: 1:1 - 1:10
UniProt Number: P42081
NCBI GenBank: NM_006889 | NP_008820.3
SwissProt: P42081

Target: Mouse CD86
Antigen Species: Mouse
Epitope: Recognizes mouse CD86 (B7-2), an 80kD cell surface glycoprotein which is a member of the CD28/B7 family. In mouse CD86 is expressed at high levels on peripheral blood monocytes and dendritic cells, and at low levels on resting B and T-lymphocytes. Expression of CD86, on these cell populations, can be increased upon activation. CD86 has been identified, along with CD80 (B7-1), as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA4). CD28 and CTLA4 are two receptors that have opposing functions in T-cell stimulation. Interaction of CD86 with CD28 promotes a number of T-cell activities, whereas the binding of CD86 to CTLA4 inhibits T-cell responses. The PO3 antibody has been reported to block some co-stimulatory functions of CD86. XXX recommend the use of MCA2463EL for this purpose.
Gene Name: CD86

Storage Conditions: Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS