LSBio
CD86 Antibody (clone BU63, RPE)

CD86 Antibody (clone BU63, RPE)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry
Reactivity:Human
Format:Lyophilized
See all Human CD86 antibodies →
$413.00each
Catalog Number: LS-C43298-100

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Overview

Description
CD86 antibody LS-C43298 is an RPE-conjugated mouse monoclonal antibody to human CD86. Validated for Flow.
Application
FC
Reactivity
Hu
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Activation B7-2 antigen | B7-2 | B7.2 | B70 | CD86 molecule | CD86 | CTLA-4 counter-receptor B7.2 | CD86 antigen | FUN-1 | LAB72 | BU63 | CD28LG2 | Ctla-4 counter-receptors b7.2
Recommended Dilution: FC
1:1 - 1:10
UniProt Number
P42081
SwissProt
P42081

Target

Target
Human CD86
Antigen Species
Hu
Epitope
Recognizes human CD86 also known as B7-2, a type I transmembrane protein expressed by monocytes and activated B cells. CD86 acts as a co-stimulatory molecule along with CD80 and is a ligand for CD28 and CTLA-4. CD86 is a member of the Immunoglobulin superfamily and carries an extracellular domain bearing both an domain which contains the CTLA-4 binding site and an adjacent C2-like domain. CD86 plays an important role in co-stimulation of T cell proliferation, IL-2 production and in the primary immune response. Domain depletion epitope mapping studies indicate that the binding site of Mouse anti Human CD86, is located within the Ig-v-like domain of human CD86. Studies suggest that CD86 along with CD80 may be exploited as receptors for adenovirus entry into cells.
Gene Name
CD86

Antibody

Host Species
Ms
Clonality
Monoclonal
Clone
BU63
Isotype
IgG1

Immunogen

Immunogen
Human peripheral blood lymphocytes.
Immunogen Type
Cell

Format

Conjugate/Label
PE
Format
Lyophilized
Formulation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Preservative
Yes
Purification Method
Prot A

Storage & Handling

Storage Conditions
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.