CD80 Antibody (clone RM80, RPE)

Name: CD80 Antibody (clone RM80, RPE)
Brand: LSBio
SKU: LS-C57975-100
Price: 413 USD
Availability: InStock

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$413.00each

Catalog Number: LS-C57975-100

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Description: CD80 antibody LS-C57975 is an RPE-conjugated rat monoclonal antibody to mouse CD80. Validated for Flow.
Application: FC
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: Activation B7-1 antigen | B7-1 | B7.1 | BB1 | CD28LG | CD28LG1 | CD80 antigen | LAB7 | CD80 | CD80 molecule | CTLA-4 counter-receptor B7.1
Recommended Dilution: FC: 1:1
UniProt Number: P33681
NCBI GenBank: NM_005191 | NP_005182.1
SwissProt: P33681

Target: Mouse CD80
Antigen Species: Mouse
Epitope: Recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses.
Gene Name: CD80

Storage Conditions: Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS