LSBio
CD80 Antibody (clone IDEC-114)

CD80 Antibody (clone IDEC-114)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Blocking / Competition Assay, Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Functional Assay, Immunohistochemistry (general), Immunoprecipitation, Western Blot
Reactivity:Human
Format:Liquid
See all Human CD80 antibodies →
$551.00each
Catalog Number: LS-C821452-0.2

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Overview

Description
This CD80 antibody is an unconjugated Rabbit/Human chimeric recombinant monoclonal antibody. Validated for Block, ELISA, Flo, Func, IHC, IP, and WB.
Application
Blocking, ELISA, FC, Func, IHC, IP, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
Activation B7-1 antigen | B7-1 | B7.1 | BB1 | CD28LG | CD28LG1 | CD80 antigen | LAB7 | CD80 | CD80 molecule | CTLA-4 counter-receptor B7.1
UniProt Number
P33681
SwissProt
P33681

Target

Target
Human CD80
Antigen Species
Human
Epitope
Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to CD80. CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.
Gene Name
CD80

Antibody

Host Species
Rabbit
Clonality
Recombinant Monoclonal
Clone
IDEC-114
Isotype
IgG
Light Chain
Lambda Light Chain
Origin Species
Human

Immunogen

Immunogen
Galiximab was prepared by immunizing cynomolgus monkeys with recombinant CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013)
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.02% Proclin 300
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store undiluted at 4°C for up to 3 months. Aliquot and store at -20°C for long term storage.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.