CD74 / CLIP Antibody (C-Terminus, clone Bu45)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunofluorescence, Immunohistochemistry, Frozen, Immunoprecipitation |
| Reactivity: | Human |
| Format: | Liquid |
$392.00each
Catalog Number: LS-C44928-0.2
Catalog Number: LS-C44928
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- CLIP antibody LS-C44928 is an unconjugated mouse monoclonal antibody to human CLIP (CD74) (C-Terminus). Validated for Flow, IF, IHC and IP.
- Application
- FC, IF, IHC-F, IP
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD74 antigen | CD74 | DHLAG | HLADG | HLA-DR-gamma | Ia-associated invariant chain | p33 | MHC HLA-DR gamma chain | Ia-GAMMA
- Recommended Dilution: FC
- 1:25 - 1:50
- UniProt Number
- P04233
- NCBI GenBank
- NM_004355 | NP_004346.1
- SwissProt
- P04233
Target
- Target
- Human CD74 / CLIP
- Antigen Species
- Human
- Epitope
- Recognizes human CD74, a type II transmembrane protein, which is also known as the MHC class II associated invariant chain. The Recognizes 33, 35 and 41 kD isoforms of CD74. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, dendritic cells and by various types of carcinoma. Expression of CD74 is primarily intracellular with moderate expression at the cell surface of B cells and monocytes. The Bu45 antibody binds to an epitope within the extracytoplasmic domain of the CD74 molecule, which is distal from the C-terminus. *Membrane permeabilization may enhance CD74 staining. XXX recommend the use of Leucoperm (product code BUF09) for this purpose.
- Gene Name
- CD74
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- Bu45
- Isotype
- IgG1
Immunogen
- Immunogen
- B lymphoblastoid cell line HFB1
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS