Paraffin-embedded mouse cancerous lung is stained with CD68 Antibody used at a 1:50 dilution.

CD68 Antibody

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot
Reactivity:	Mouse, Rat
Format:	Liquid

$441.00each

Catalog Number: LS-C414173-0.1

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Description: CD68 antibody LS-C414173 is an unconjugated rabbit polyclonal antibody to CD68 from mouse. It is reactive with mouse and rat. Validated for ELISA, IF, IHC and WB.
Application: ELISA, IF, IHC, WB
Reactivity: Ms, Rt
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: CD68 antigen | gp110 | SCARD1 | CD68 | CD68 molecule | LAMP4 | Macrophage antigen CD68 | Macrosialin
Recommended Dilution: ELISA: 1:500 - 1:1000
Recommended Dilution: IF/ICC: 1:100 - 1:500
Recommended Dilution: IHC: 1:200 - 1:500
Recommended Dilution: WB: 1:200 - 1:500
UniProt Number: P34810
NCBI GenBank: NM_001251 | NP_001242.2
SwissProt: P34810

Target: Mouse CD68
Antigen Species: Mouse
Epitope: The CD68 antigen is involved in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 binds to tissue- and organ-specific lectins and selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane helps macrophages to move over selectin-bearing substrates and other cells. CD68 is highly expressed by blood monocytes and tissue macrophages as well as many tumor cell lines promoting binding to selectins on vascular endothelium facilitating dissemination to secondary sites.
Gene Name: CD68