Flow cytometry of mouse peritoneal macrophages cells with Rat anti-Mouse CD68:Biotin .following permeablisation with Leucoperm This image was taken for the unconjugated form of this product. Other forms have not been tested.

CD68 Antibody (clone FA-11, Biotin)

Primary AntibodyLSBio Guarantee

Antibody:	Rat Monoclonal
Applications:	Immunohistochemistry, Frozen
Reactivity:	Mouse
Format:	Liquid

$401.00each

Catalog Number: LS-C188200-0.1

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Overview

Description: CD68 antibody LS-C188200 is a biotin-conjugated rat monoclonal antibody to mouse CD68. Validated for IHC.
Application: IHC-F
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD68 antigen | gp110 | SCARD1 | CD68 | CD68 molecule | LAMP4 | Macrophage antigen CD68 | Macrosialin
UniProt Number: P34810
NCBI GenBank: NM_001251 | NP_001242.2
SwissProt: P34810

Target

Target: Mouse CD68
Antigen Species: Mouse
Epitope: Macrosialin is a heavily glycosylated transmembrane protein of 87-115kD, which is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. Macrosialin is the murine homologue of the human macrophage glycoprotein CD68, both are members of the lysosomal-associated membrane protein (LAMP) family which are located predominantly within the cells and can be detected by flow cytometry using cell permeabilization. The antibody does detect surface macrosialin at low levels in resident mouse peritoneal macrophages which can be enhanced with thioglycollate stimulation.
Gene Name: CD68

Antibody

Host Species: Rat
Clonality: Monoclonal
Clone: FA-11
Isotype: IgG2a

Immunogen

Immunogen: Purified Concanavalin A acceptor glycoprotein from P815 cell line.
Immunogen Type: Cell-Based Immunization

Format

Conjugate/Label: Biotin
Format: Liquid
Formulation: PBS, 0.09% Sodium Azide, 1% BSA
Concentration: 0.1 mg/mL
Preservative: Yes
Purification Method: Protein G Affinity

Storage & Handling

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS