CD55 Antibody (clone 67)

Antibody:	Mouse Monoclonal
Applications:	Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Western Blot
Reactivity:	Human
Format:	Liquid

$286.00each

Catalog Number: LS-C11548-0.1

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Description: CD55 antibody LS-C11548 is an unconjugated mouse monoclonal antibody to human CD55. Validated for Flow, IHC and WB.
Application: FC, IHC, IHC-F, WB
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD55 | CD55 antigen | Decay-accelerating factor | TC | CR | CROM | DAF
Recommended Dilution: FC: 1:10 - 1:25
Recommended Dilution: IHC-F: 1:100 - 1:1000
UniProt Number: P08174
NCBI GenBank: NM_000574 | NP_000565.1
SwissProt: P08174

Target: Human CD55
Antigen Species: Human
Epitope: Recognizes the human CD55 cell surface antigen, a GPI linked molecule also known as decay accelerating factor (DAF). CD55 is expressed by a wide range of cell types. Erythrocyte expression is very weak. CD55 is the complement regulatory protein, decay accelerating factor (DAF). Human CD55 is a ~70kD glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail. In other cells the apparent molecular weight is somewhat larger. It has a substantial content of O-glycans, and also on N-glycan. DAF binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways. DAF carries the Cromer related blood group antigens. DAF has a wide distribution on cells in non-hemopoietic tissues, particularly epithelium and is specifically found at the fetal-maternal interface in placenta and. Soluble forms of DAF are found, for example, in plasma, saliva and urine. The antigen on erythrocytes is pronase and chymotrypsin sensitive, but resistant to trypsin.
Gene Name: CD55

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS