LSBio
CD52 Antibody (clone YTH34.5, Low Endotoxin)

Flow cytometry of human peripheral blood lymphocytes with Rat anti-Human CD52: Low Endotoxin This image was taken for the unmodified form of this product. Other forms have not been tested.

CD52 Antibody (clone YTH34.5, Low Endotoxin)

Primary AntibodyLSBio Guarantee
Antibody:Rat Monoclonal
Applications:Cytotoxicity Assay, Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:Human
Format:Liquid
See all Human CD52 antibodies →
$691.00each
Catalog Number: LS-C188149-0.5

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Overview

Description
CD52 antibody LS-C188149 is an unconjugated rat monoclonal antibody to human CD52. Validated for Ctox, ELISA, Flow, IHC, IP and WB.
Application
CTA, ELISA, FC, IHC, IHC-F, IHC-P, IP, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Cambridge pathology 1 antigen | CD52 antigen | CD52 molecule | CDW52 | CD52 | He5
Recommended Dilution: FC
1:50 - 1:100
UniProt Number
P31358
SwissProt
P31358

Target

Target
Human CD52
Antigen Species
Human
Epitope
Reacts with the human CD52 antigen, also known as CAMPATH-1. The CD52 antigen is a remarkably small but heavily glycosylated peptide attached to the cell surface membrane via a GPI link. The apparent molecular mass of the native antigen on SDS-PAGE is 25-29kD, considerably reduced following N-glycanase treatment. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. Humanized versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies ;.
Gene Name
CD52

Antibody

Host Species
Rat
Clonality
Monoclonal
Clone
YTH34.5
Isotype
IgG2b

Immunogen

Immunogen
Human lymphocytes.
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS
Concentration
1 mg/mL
Preservative
No
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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