Formalin-fixed, paraffin-embedded human Lymph Node stained with CD45RB Rabbit Recombinant Monoclonal Antibody (PTPRC/2877R).

CD45RB Antibody (clone PTPRC/2877R, Azide-free, Carrier-free)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Recombinant Monoclonal
Applications:	Flow Cytometry, Immunofluorescence, Immunohistochemistry, Paraffin, Western Blot
Reactivity:	Human
Format:	Liquid

$586.00each

Catalog Number: LS-C751335-100

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Overview

Description: CD45RB antibody LS-C751335 is an unconjugated rabbit recombinant monoclonal antibody to human CD45RB. Validated for Flow, IF, IHC and WB.
Application: FC, IF, IHC-P, WB
Reactivity: Hu
Nonreactive Species: Rat, Rhesus Macaque
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Recommended Dilution: FC: 1 - 2 µg/10E6 cells
Recommended Dilution: IF/ICC: 1 - 2 µg/ml
Recommended Dilution: IHC-P: 1 - 2 µg/ml
Recommended Dilution: WB: 1 - 2 µg/ml

Target

Target: Human CD45RB
Antigen Species: Human
Epitope: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.