CD3E Antibody (clone 145-2C11)

Primary AntibodyLSBio Guarantee

Antibody:	Hamster Monoclonal
Applications:	Flow Cytometry, Immunofluorescence, Immunohistochemistry, Frozen, Immunoprecipitation, Western Blot
Reactivity:	Mouse
Format:	Liquid

$392.00each

Catalog Number: LS-C45012-0.25

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Description: CD3E antibody LS-C45012 is an unconjugated hamster monoclonal antibody to mouse CD3E. Validated for Flow, IF, IHC, IP and WB.
Application: FC, IF, IHC-F, IP, WB
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD3e antigen | CD3E | CD3-epsilon | T-cell receptor epsilon chain | TCRE | T-cell receptors epsilon chain | T3E | CD3 Epsilon | CD3
NCBI GenBank: NM_000733 | NP_000724.1

Target: Mouse CD3E
Antigen Species: Mouse
Epitope: Detects CD3 epsilon (CD3e), a 20kD transmembrane protein also known as CD3 or T3. CD3e is a member of the CD3 complex which consists of four subunits, gamma, delta, epsilon and zeta, and these are associated to the T cell receptor (TCR). TCR plays a critical role in T cell development and function, and is responsible for ligand recognition. It interacts non-covalently with the CD3 dimers delta/epsilon, gamma/epsilon and zeta/zeta which transduce signals from the TCR into the cell. CD3e is primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. The 145-2C11 antibody is useful for in vitro blocking and activation assays, as well as apoptosis induction and in vitro T cell depletions.

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS