Formalin-fixed, paraffin-embedded human Tonsil stained with CD27 Mouse Recombinant Monoclonal Antibody (rLPFS2/1611).

CD27 Antibody (clone rLPFS2/1611, Azide-free, Carrier-free)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Recombinant Monoclonal
Applications:	Flow Cytometry, Immunohistochemistry, Paraffin
Reactivity:	Human
Format:	Liquid

$586.00each

Catalog Number: LS-C751447-100

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Overview

Description: CD27 antibody LS-C751447 is an unconjugated mouse recombinant monoclonal antibody to human CD27. Validated for Flow and IHC.
Application: FC, IHC-P
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: CD27 | CD27 antigen | CD27 molecule | S152 | T14 | T-cell activation antigen CD27 | CD27L receptor | T cell activation antigen S152 | TNFRSF7 | Tp55
Recommended Dilution: FC: 1 - 2 µg/10E6 cells
Recommended Dilution: IHC-P: 1 - 2 µg/ml
UniProt Number: P26842
NCBI GenBank: NM_001242 | NP_001233.1
SwissProt: P26842

Target

Target: Human CD27
Antigen Species: Human
Epitope: Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.
Gene Name: CD27