LSBio
CD22 Antibody (CD22, clone hL22 (Epratuzumab))

Flow-cytometry on rhesus monkey lymphocytes.

CD22 Antibody (CD22, clone hL22 (Epratuzumab))

Primary AntibodyLSBio Guarantee
Antibody:Human Recombinant Monoclonal
Applications:Blocking / Competition Assay, Flow Cytometry, Immunoprecipitation
Reactivity:Cynomolgus Monkey, Human, Rhesus Macaque
Format:Liquid
See all Human CD22 antibodies →
$551.00each
Catalog Number: LS-C777525-0.2

For bulk orders or custom formulations:

Request a Quote

Overview

Description
This CD22 antibody is an unconjugated Human/Human chimeric recombinant monoclonal antibody. Validated for Block, Flo, and IP.
Application
Blocking, FC, IP
Reactivity
Cyno, Hu, Rhes
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
CD22 molecule | CD22 | CD22 antigen | SIGLEC2 | SIGLEC-2 | T-cell surface antigen Leu-14 | B-cell receptor CD22 | BL-CAM
UniProt Number
P20273
SwissProt
P20273

Target

Target
Human CD22
Antigen Species
Human
Epitope
This antibody is specific for the 3rd Ig-like domain of human CD22 (epitope B), a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells.
Gene Name
CD22

Antibody

Host Species
Human
Clonality
Recombinant Monoclonal
Clone
hL22 (Epratuzumab)
Isotype
IgG1
Light Chain
Kappa Light Chain
Origin Species
Human

Immunogen

Immunogen
This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5-10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010).
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.02% ProClin™ 300.
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.