LSBio
CD22 Antibody (CD22, clone hL22 (Epratuzumab))

Flow-cytometry on rhesus monkey lymphocytes.

CD22 Antibody (CD22, clone hL22 (Epratuzumab))

Primary AntibodyLSBio Guarantee
Antibody:Human Recombinant Monoclonal
Applications:Blocking / Competition Assay, Flow Cytometry, Immunoprecipitation
Reactivity:Cynomolgus Monkey, Human, Rhesus Macaque
Format:Liquid
See all Human CD22 antibodies →
$551.00each
Catalog Number: LS-C777525-0.2

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Overview

Description
This CD22 antibody is an unconjugated Human/Human chimeric recombinant monoclonal antibody. Validated for Block, Flo, and IP.
Application
Blocking, FC, IP
Reactivity
Cyno, Hu, Rhes
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
CD22 molecule | CD22 | CD22 antigen | SIGLEC2 | SIGLEC-2 | T-cell surface antigen Leu-14 | B-cell receptor CD22 | BL-CAM
UniProt Number
P20273
SwissProt
P20273

Target

Target
Human CD22
Antigen Species
Hu
Epitope
This antibody is specific for the 3rd Ig-like domain of human CD22 (epitope B), a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells.
Gene Name
CD22

Antibody

Host Species
Hu
Clonality
Recombinant Monoclonal
Clone
hL22 (Epratuzumab)
Isotype
IgG1
Light Chain
κ
Origin Species
Hu

Immunogen

Immunogen
This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5-10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010).
Immunogen Type
Cell

Format

Conjugate/Label
Unconj
Format
Liquid
Formulation
PBS, 0.02% ProClin™ 300.
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Prot A

Storage & Handling

Storage Conditions
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Recommended Storage Buffer
PBS

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