LSBio
CD110 / MPL Antibody (aa615-628)

WB: DAMI cell lysate probed with Thrombopoietin Receptor (c-Mpl) (TPO) (0.5 ug/ml).

CD110 / MPL Antibody (aa615-628)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunoprecipitation, Western Blot
Reactivity:Hamster, Human, Mouse, Non-Human Primate
Format:Liquid
See all Human CD110 / MPL antibodies →
$859.00each
Catalog Number: LS-C26341-200

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Overview

Description
MPL antibody LS-C26341 is an unconjugated rabbit polyclonal antibody to MPL (CD110) (aa615-628) from human. It is reactive with human, mouse, hamster and other species. Validated for IHC, IP and WB. Cited in 1 publication.
Application
IHC, IP, WB
Reactivity
Ham, Hu, Ms, NHP
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CD110 antigen | C-MPL | CD110 | MPL | MPLV | Proto-oncogene c-Mpl | TPOR | TPO-R | THCYT2 | Thrombopoietin receptor
UniProt Number
P40238
SwissProt
P40238

Target

Target
Human CD110 / MPL
Antigen Species
Human
Epitope
Recognizes glycosylated and unglycosylated human TPO receptor/c-Mpl, Mr 70kD. Species cross-reactivity: mouse. Species sequence Homology: mouse - 100%.
Gene Name
MPL

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Synthetic peptide corresponding to amino acids 615-628 of human TPO (thrombopoietin) receptor [C-ANHSYLPLSYWQQP] (KLH-conjugated). Species sequence Homology: Mouse - 100%. Percent identity by BLAST analysis: Human, Monkey, Mouse, Hamster (100%); Elephant, Rabbit (93%); Panda, Bovine, Pig (86%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
0.1 M Tris-Glycine, pH 7.4, 0.15 M NaCl, 0.05% Sodium Azide, 30% Glycerol
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
0.1 M Tris-Glycine|0.15 M NaCl
MPL immunohistochemical expression as a novel marker for essential thrombocythemia and primary myelofibrosis differential diagnosis. Ponce CC, Chauffaille, Ihara SS, Silva MR. Leukemia research. 2012 Jan;36:93-7. PubMed: 21752469

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