LSBio
CD11 + CD18 Antibody (clone 24, FITC)

CD11 + CD18 Antibody (clone 24, FITC)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunocytochemistry, Immunofluorescence
Reactivity:Human
Format:Liquid
See all Human CD11 + CD18 antibodies →
$647.00each
Catalog Number: LS-C827860-50

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Overview

Description
CD11 + CD18 antibody LS-C827860 is an FITC-conjugated mouse monoclonal antibody to human CD11 + CD18. Validated for Flow, ICC and IF.
Application
FC, ICC, IF
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies

Target

Target
Human CD11 + CD18
Antigen Species
Human
Epitope
This antibody recognizes integrin alpha L,M,X/Beta 2 (CD11/CD18). Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits which mediate cell-cell and cell-extracellular matrix attachments. Integrin beta2 (CD18) associates with integrin alpha L (CD11a) to form the leukocyte function-associated antigen-1 (LFA-1) with integrin alpha M (CD11b) to form Complement Receptor 3 (CR3) and with integrin alpha X (CD11c) to form Complement Receptor 4 (CR4). Each integrin receptor can bind various Intercellular adhesion molecules (ICAMs). Aberrant integrin expression has been found in many epithelial tumors. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
24
Isotype
IgG1

Immunogen

Immunogen
Fibronectin-purified human monocytes.
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Fluorescein Isothiocyanate
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
0.9 mg/mL
Volume
50 Microliter
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.