Positive WB detected in:HEK293 whole cell lysate,PC3 whole cell lysate,Mouse kidney tissue,Mouse brain tissue;All lanes:CBR1 antibody at 2.5ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 31,19 kDa;Observed band size: 31 kDa;
CBR / CBR1 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C498516-50
Catalog Number: LS-C498516
For bulk orders or custom formulations:
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- Description
- CBR1 antibody LS-C498516 is an unconjugated rabbit polyclonal antibody to CBR1 (CBR) from human. It is reactive with human and mouse. Validated for ELISA, IF and WB.
- Application
- ELISA, IF, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Carbonyl reductase 1 | Carbonyl reductase (NADPH) 1 | CBR1 | HCBR1 | Prostaglandin 9-ketoreductase | SDR21C1 | Carbonyl reductase [NADPH] 1 | CBR | CRN | Prostaglandin-E(2) 9-reductase
- UniProt Number
- P16152
- NCBI GenBank
- NM_001757 | NP_001748.1
- SwissProt
- P16152
Target
- Target
- Human CBR / CBR1
- Antigen Species
- Human
- Epitope
- NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
- Gene Name
- CBR1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Carbonyl reductase [NADPH] 1 protein (176-268AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS