Formalin-fixed, paraffin-embedded sections from a brain tumor tissue array stained for Caspase-8 expression using Polyclonal Antibody to Caspase-8 (Pro and Active) at 1:2000. A. Anaplastic glioma cores from two different patients, positive (left) and negative (right) staining for caspase-8. B. Higher magnification from the caspase-8 positive (A, left) core.
CASP8 / Caspase 8 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$394.00each
Catalog Number: LS-C148246-50
Catalog Number: LS-C148246
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- Caspase 8 antibody LS-C148246 is an unconjugated rabbit polyclonal antibody to human Caspase 8 (CASP8). Validated for IHC, IP and WB.
- Application
- IHC, IHC-F, IHC-P, IP, WB
- Reactivity
- Hu
- Predicted Reactivity
- Non-Human Primate
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- ALPS2B | Apoptotic protease Mch-5 | Apoptotic cysteine protease | Casp-8 | Caspase-8 | CAP4 | Caspase 8 | MACH | MCH5 | MORT1-associated ced-3 homolog | ICE-like apoptotic protease 5 | Pro Caspase 8 | CASP8 | FADD-like ICE | FLICE | MACH-alpha-1/2/3 protein | MACH-beta-1/2/3/4 protein
- Recommended Dilution: IHC-P
- 1:1000 - 1:5000
- Recommended Dilution: IP
- 1:50 - 1:200
- Recommended Dilution: WB
- 1:1000 - 1:2000
- UniProt Number
- Q14790
- NCBI GenBank
- AAC50645.1 | nm_001228
- SwissProt
- Q14790
Target
- Target
- Human CASP8 / Caspase 8
- Antigen Species
- Human
- Epitope
- Caspase-8.
- Gene Name
- CASP8
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- Peptide sequence corresponding to the C-Terminus of human Caspase-8 (PQPTFTLRKKLVFPSD). This sequence is common to various Caspase-8 forms including Caspase 8a (aa481-496), Caspase 8b (aa464-479), Caspase 8c (aa449-464), Caspase8L (aa523-538), Truncated caspase 8 (as251-266). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (94%); Orangutan, Mouse, Bovine, Dog, Bat, Elephant, Panda, Horse, Pig (81%).
- Immunogen Type
- Peptide
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- Antiserum, 0.05% sodium azide
- Volume
- 50 Microliter
- Preservative
- Yes
- Purification Method
- Unpurified (Serum / Ascites / Supernatant)
Storage & Handling
- Storage Conditions
- Store at -20°C. Aliquot to avoid freeze/thaw cycles.