Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma Stained with RCC Rabbit Recombinant Monoclonal Antibody (CA9/2993R).
CA9 / Carbonic Anhydrase IX Antibody (clone CA9/2993R)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751423-20
Catalog Number: LS-C751423
For bulk orders or custom formulations:
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- Description
- Carbonic Anhydrase IX antibody LS-C751423 is an unconjugated rabbit recombinant monoclonal antibody to human Carbonic Anhydrase IX (CA9). Validated for IHC.
- Application
- IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- CA9 | CAIX | Carbonate dehydratase IX | Carbonic anhydrase IX | CA-IX | Carbonic dehydratase | G250 | MN | Membrane antigen MN | p54/58N | RCC-associated antigen G250 | RCC-associated protein G250 | Carbonic anhydrase 9 | PMW1 | CA IX
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- Q16790
- NCBI GenBank
- NM_001216 | NP_001207.2
- SwissProt
- Q16790
Target
- Target
- Human CA9 / Carbonic Anhydrase IX
- Antigen Species
- Human
- Epitope
- Recognizes a glycoprotein of ~200 kDa , identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
- Gene Name
- CA9
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- CA9/2993R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human CA9 protein. Antigen Molecular Weight: 55 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS