LSBio
C5AR1 / CD88 / C5a Receptor Antibody

Positive WB detected in: PC-3 whole cell lysate,HepG-2 whole cell lysate,HEK293 whole cell lysate;All lanes: C5AR1 antibody at 30ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000000 dilution;Predicted band size: 40 kDa;Observed band size: 40 kDa;

C5AR1 / CD88 / C5a Receptor Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Western Blot
Reactivity:Human
Format:Liquid
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$300.00each
Catalog Number: LS-C498480-50

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Overview

Description
C5a Receptor antibody LS-C498480 is an unconjugated rabbit polyclonal antibody to human C5a Receptor (C5AR1 / CD88). Validated for ELISA, IF and WB.
Application
ELISA, IF, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
C5A | C5a-R | C5a ligand | C5a receptor | CD88 | C5a anaphylatoxin receptor | C5AR | C5AR1 | C5R1 | CD88 antigen
UniProt Number
P21730
SwissProt
P21730

Target

Target
Human C5AR1 / CD88 / C5a Receptor
Antigen Species
Human
Epitope
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
Gene Name
C5AR1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant human C5a anaphylatoxin chemotactic receptor 1 protein (1-36AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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