c-Kit / CD117 Antibody (clone 2B8/BM)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunoprecipitation, Western Blot |
| Reactivity: | Pig |
| Format: | Liquid |
$363.00each
Catalog Number: LS-C187513-0.1
Catalog Number: LS-C187513
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- Description
- CD117 antibody LS-C187513 is an unconjugated mouse monoclonal antibody to pig CD117 (c-Kit). Validated for Flow, IHC, IP and WB.
- Application
- FC, IHC, IHC-F, IP, WB
- Reactivity
- Por
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- C-Kit | CD117 | KIT | PBT | Piebald trait | Piebald trait protein | Proto-oncogene c-Kit | SCFR | Soluble KIT variant 1 | Tyrosine-protein kinase Kit | p145 c-kit | CD117 antigen
- UniProt Number
- P10721
- NCBI GenBank
- NM_000222 | NP_000213.1
- SwissProt
- P10721
Target
- Target
- Pig c-Kit / CD117
- Antigen Species
- Pig
- Epitope
- Porcine CD117, also known as c-kit, a 155kD type I transmembrane protein with protein tyrosine kinase activity, which plays an important role in early hematopoiesis. Hematopoietic stem cells (HSC) of bone marrow have multilineage differentiation potential and an extensive capacity for self-renewal. The majority of adult bone marrow hematopoietic progenitor cells are CD117+ and have been used successfully in xenograft transplantation models for long term survival of grafts, without symptoms of graft-versus-host disease (GVHD). Recognizes CD117 on a small subset of porcine bone marrow progenitor cells and therefore provides an alternative tool from the previously used c-kit ligand stem cell factor, for the isolation and enrichment of porcine stem cells.
- Gene Name
- KIT
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 2B8/BM
- Isotype
- IgG1
Immunogen
- Immunogen
- Porcine bone marrow cells (BMC).
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS