LSBio
BMP6 Antibody (clone morph-6.1, Biotin)

BMP6 Antibody (clone morph-6.1, Biotin)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Frozen
Reactivity:Rat
Format:Lyophilized
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$847.00each
Catalog Number: LS-C96419-100

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Overview

Description
BMP6 antibody LS-C96419 is a biotin-conjugated mouse monoclonal antibody to rat BMP6. Validated for IHC.
Application
IHC, IHC-F
Reactivity
Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
BMP6 | BMP-6 | Bone morphogenetic protein 6 | VG-1-related protein | VGR1 | VG-1-R | VGR | Vg1 | Vg1-related sequence | VGR-1
Recommended Dilution: IHC-F
1:100 - 1:200
UniProt Number
P22004
SwissProt
P22004

Target

Target
Rat BMP6
Antigen Species
Rat
Epitope
Bone morphogenic protein 6. Pre-incubation of morph-6.1 with amino-terminal peptide 1-29 of BMP-6 inhibits binding of the antibody to tissue sections. Pre-incubation with other amino- terminal synthetic peptides of human BMP-7, BMP-4, BMP-3 and BMP-2 as well as an irrelevant peptide does not inhibit specific tissue staining. Antigen distribution: Tissue sections: Positive staining can be observed in embryonic and adult central nervous system. Rat radial glial cells of the developing central nervous system from E11 to E19. In rat peripheral nerves a selective intracellular immunoreactivity can be found in perinuclear region of most Schwann cells which form the myelin sheath. However, some Schwann cells were negative for morph-6.1. BMP-6 can also be found in a variety of other tissues and cell types, notably keratinizing epithelial cells. Smooth muscle cells, characterized by Desmin positivity, were positively stained in normal tissues and in atherosclerotic plaques. Macrophages (CD68+) and endothelial cells were negative with morph-6.1. Specificity: Rat: Bone morphogenic Protein-6 (BMP-6) Synonyms are: vgr-1 (vegetal related) or DVR-6 (decapentaplegic vegetal related). Other species: phylogenetically highly conserved (human positive)
Gene Name
BMP6

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
morph-6.1
Origin Species
Human

Immunogen

Immunogen
Aminoterminal synthetic peptide 1-29-KLh
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Biotin
Format
Lyophilized
Formulation
Lyophilized from PBS pH 7.2, 5mg/ml BSA, 0.09%sodium azide
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.