LSBio
BLNK Antibody (aa171-356, Concentrated)

BLNK Antibody (aa171-356, Concentrated)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Western Blot
Reactivity:Mouse
Format:Liquid
See all Mouse BLNK antibodies →
$556.00each
Catalog Number: LS-C202774-0.1

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Overview

Description
BLNK antibody LS-C202774 is an unconjugated rabbit polyclonal antibody to mouse BLNK (aa171-356). Validated for WB.
Application
WB
Reactivity
Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
AGM4 | BLNK-S | B-cell activation | B-cell linker protein | BLNK | B cell linker protein | Bca | Cytoplasmic adapter protein | LY57 | SLP-65 | SLP65 | B-cell linker | BASH
UniProt Number
Q8WV28
SwissProt
Q8WV28

Target

Target
Mouse BLNK
Antigen Species
Mouse
Epitope
BLNK (B cell linker protein) is an adaptor molecule that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). This activation leads to an increase in the tyrosine phosphorylation of a number of proteins due to activation of nonreceptor protein tyrosine kinases (PTK) including Syk, which is responsible for the tyrosine phosphorylation of BLNK. BLNK is cytosolic protein identified as two phosphoproteins migrating at 68 and 70 kD in SDS/PAGE (alternatively spliced forms of human BLNK). Mapping of the tyrosine residues in BLNK reveal three tyrosines that bind PLC-gamma2, and two tyrosines that bind the Tec family kinase Btk, the Vav nucleotide exchange factor and the adaptor Nck.
Gene Name
BLNK

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
A fusion protein representing amino acids 171-356 of human BLNK.
Immunogen Type
Fusion Protein (e.g., GST, MBP tag)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 15 mM Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Other

Storage & Handling

Storage Conditions
Store at 2-8°C.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.