Immunohistochemistry of paraffin-embedded human lung cancer using BCL2 Antibody at dilution of 1:100
BCL2 / Bcl-2 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general) |
| Reactivity: | Human |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C500256-50
Catalog Number: LS-C500256
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- Description
- Bcl-2 antibody LS-C500256 is an unconjugated rabbit polyclonal antibody to human Bcl-2 (BCL2). Validated for ELISA, IF and IHC.
- Application
- ELISA, IF, IHC
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- Apoptosis regulator Bcl-2 | BCL2 | B-cell CLL/lymphoma 2 | B-cell lymphoma protein 2 | Bcl-2 | PPP1R50
- UniProt Number
- P10415
- NCBI GenBank
- NM_000633 | NP_000624.2
- SwissProt
- P10415
Target
- Target
- Human BCL2 / Bcl-2
- Antigen Species
- Human
- Epitope
- Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
- Gene Name
- BCL2
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Apoptosis regulator Bcl-2 protein (31-80AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS