BCL10 / BCL-10 Antibody (aa122-168, clone 151)

Name: BCL10 / BCL-10 Antibody (aa122-168, clone 151)
Brand: LSBio
SKU: LS-C95617-0.1
Price: 281 USD
Availability: InStock

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$281.00each

Catalog Number: LS-C95617-0.1

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Description: BCL-10 antibody LS-C95617 is an unconjugated mouse monoclonal antibody to human BCL-10 (BCL10) (aa122-168).
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: BCL10 | Bcl-10 | B-cell CLL/lymphoma 10 | B-cell lymphoma/leukemia 10 | CARMEN | CARD-like apoptotic protein | CCARMEN | C-E10 | CIPER | Cellular-E10 | HCLAP | Cellular homolog of vCARMEN | CLAP | ME10
UniProt Number: O95999
NCBI GenBank: NM_003921 | NP_003912.1
SwissProt: O95999

Target: Human BCL10 / BCL-10
Antigen Species: Human
Epitope: Monoclonal Anti-Bcl-10 reacts specifically with human Bcl-10. The epitope recognized by the antibody resides within amino acids 122-168 of human Bcl-10 molecule. Bcl-10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (Caspase Recruitment Domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (vCLAP). Bcl-10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl-10 cellular overexpression induces JNK, p38, and NF-kB activation. Deregulation of Bcl-10 expression is also demonstrated to be involved in cellular oncogenesis.
Gene Name: BCL10

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