BANF1 / BAF / BCRP1 Antibody (Biotin)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C498446-50

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Description: BCRP1 antibody LS-C498446 is a biotin-conjugated rabbit polyclonal antibody to human BCRP1 (BANF1 / BAF). Validated for ELISA.
Application: ELISA
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: BANF1 | BCRG1 | BCRP1 | NGPS | BAF | D14S1460
UniProt Number: O75531
NCBI GenBank: NM_003860 | NP_003851.1
SwissProt: O75531

Target: Human BANF1 / BAF / BCRP1
Antigen Species: Human
Epitope: Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD.
Gene Name: BANF1

Immunogen: Recombinant Human Barrier-to-autointegration factor protein (2-89AA)
Immunogen Type: Recombinant Immunogen

Storage Conditions: Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer: PBS

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