Formalin-fixed, paraffin-embedded human Bladder Carcinoma stained with Beta-2-Microglobulin Rabbit Recombinant Monoclonal Antibody (B2M/1857R).
B2M / Beta 2 Microglobulin Antibody (clone B2M/1857R)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry (general), Sodium Dodecyl-Sulfate Polyacrylamide Gel Electrophoresis / Purity Check |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751324-20
Catalog Number: LS-C751324
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- Description
- Beta 2 Microglobulin antibody LS-C751324 is an unconjugated rabbit recombinant monoclonal antibody to human Beta 2 Microglobulin (B2M). Validated for IHC and SDS-PAGE.
- Application
- IHC, SDS-PAGE
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- B2M | Beta 2 Microglobulin | Beta-2-microglobulin | Beta-2-microglobin
- Recommended Dilution: IHC-P
- 0.5-1 ug/ml
- UniProt Number
- P61769
- NCBI GenBank
- NM_004048 | NP_004039.1
- SwissProt
- P61769
Target
- Target
- Human B2M / Beta 2 Microglobulin
- Antigen Species
- Human
- Epitope
- Recognizes a protein of 12 kDa , identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
- Gene Name
- B2M
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- B2M/1857R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human B2M protein. Antigen Molecular Weight: 12 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS