LSBio
Aprataxin / APTX Antibody

Immunohistochemistry of paraffin-embedded human gastric cancer using APTX Antibody at dilution of 1:100

Aprataxin / APTX Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all Human Aprataxin / APTX antibodies →
$300.00each
Catalog Number: LS-C498389-50

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Overview

Description
APTX antibody LS-C498389 is an unconjugated rabbit polyclonal antibody to human APTX (Aprataxin). Validated for ELISA and IHC.
Application
ELISA, IHC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
AOA1 | APTX | AXA1 | EAOH | EOAHA | FHA-HIT | AOA | Aprataxin
UniProt Number
Q7Z2E3
SwissProt
Q7Z2E3

Target

Target
Human Aprataxin / APTX
Antigen Species
Human
Epitope
DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity.
Gene Name
APTX

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Aprataxin protein (92-161AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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