Western Blot: beta Amyloid Antibody (MOAB-2) - Western blot of beta Amyloid (MOAB-2) antibody in 1) 100 pmole beta Amyloid 42, 2) 5xFAD mouse brain homogenate Repetition 1 and 3) 5xFAD mouse brain homogenate Repetition 2. This image was taken for the unconjugated form of this product. Other forms have not been tested.
APP / Beta Amyloid Precursor Antibody (clone MOAB-2)
| Antibody: | Mouse Monoclonal |
| Applications: | Immunocytochemistry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- Beta Amyloid Precursor antibody LS-C181965 is an unconjugated mouse monoclonal antibody to Beta Amyloid Precursor (APP) from human. It is reactive with human, mouse and rat. Validated for ICC, IHC and WB. Cited in 2 publications.
- Application
- ICC, IHC, IHC-P, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- ABPP | A4 | ABETA | AD1 | Alzheimer disease | Amyloid beta | APP | Beta-amyloid peptide | APPI | Beta amyloid | CVAP | AAA | PN2 | PreA4 | Amyloid beta A4 protein | Peptidase nexin-II | CTFgamma | PN-II | Protease nexin-II
- Recommended Dilution: IHC-P
- 1:200 - 1:1000
- UniProt Number
- P05067
- NCBI GenBank
- NM_000484 | NP_000475.1
- SwissProt
- P05067
Target
- Target
- Human APP / Beta Amyloid Precursor
- Antigen Species
- Human
- Epitope
- Unaggregated, oligomeric and fibrillar forms of beta Amyloid 42 and unaggregated beta Amyloid 40. Does not detect APP.
- Gene Name
- APP
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- MOAB-2
- Isotype
- IgG2b
Immunogen
- Immunogen
- Recombinant human beta Amyloid 42.
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.05% Sodium Azide
- Concentration
- 1 mg/mL
- Volume
- 0.1 Milliliter
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Platelets are responsible for the accumulation of ß-amyloid in blood clots inside and around blood vessels in mouse brain after thrombosis. Kucheryavykh LY, Dávila-Rodríguez J, Rivera-Aponte DE, Zueva LV, Washington AV, Sanabria P, Inyushin MY. Brain research bulletin. 2017 January;128:98-105.
PubMed: 27908798 · PMC: PMC5205543
Amyloid Beta Peptide Is Released during Thrombosis in the Skin. Kucheryavykh LY, Kucheryavykh YV, Washington AV, Inyushin MY. International journal of molecular sciences. 2018 June;19:pii: E1705.
PubMed: 29890636 · PMC: PMC6032379