Western blot of AIF in human colon using AIFM1 / AIF / PDCD8 Antibody at 1:2000. Lane 1, normal colon. Lanes 2-7, colon carcinoma tissue lysates from 6 different patients. mAIF, thought to represent mitochondrial AIF.
AIFM1 / AIF / PDCD8 Antibody (aa151-169)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot |
| Reactivity: | Bovine, Dog, Hamster, Horse, Human, Mammal (Other), Mouse, Non-Human Primate, Pig, Rabbit, Rat |
| Format: | Liquid |
$394.00each
Catalog Number: LS-C147989-50
Catalog Number: LS-C147989
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- Description
- PDCD8 antibody LS-C147989 is an unconjugated rabbit polyclonal antibody to PDCD8 (AIFM1 / AIF) (aa151-169) from human. It is reactive with human, mouse, rat and other species. Validated for IHC, IP and WB. Cited in 1 publication.
- Application
- IHC, IHC-F, IHC-P, IP, WB
- Reactivity
- Bov, Can, Ham, Hr, Hu, Mml, Ms, NHP, Por, Rb, Rt
- Predicted Reactivity
- Chicken
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- AIF | AIFM1 | COXPD6 | PDCD8 | Programmed cell death 8
- Recommended Dilution: IHC-P
- 1:1000 - 1:5000
- Recommended Dilution: IP
- 1:50 - 1:200
- Recommended Dilution: WB
- 1:1000 - 1:2000
- UniProt Number
- O95831
- NCBI GenBank
- NM_004208 | NP_004199.1
- SwissProt
- O95831
Target
- Target
- Human AIFM1 / AIF / PDCD8
- Antigen Species
- Human
- Epitope
- Human AIFM1 / AIF.
- Gene Name
- AIFM1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- Synthetic peptide corresponding to amino acids 151-169 (RARDPGARVLIVSEDPELP) of human AIF. Human AIF is a 613 aa protein. The immunogen sequence is 100% conserved in human AIF short isoforms 2 and 3. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Cat, Hamster, Elephant, Panda, Horse, Rabbit, Pig (100%); Opossum, Turkey, Chicken (95%); Xenopus (84%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- Antiserum, 0.05% sodium azide
- Volume
- 50 Microliter
- Preservative
- Yes
- Purification Method
- Unpurified (Serum / Ascites / Supernatant)
Storage & Handling
- Storage Conditions
- Store at -20°C. Aliquot to avoid freeze/thaw cycles.
AIF inhibits tumor metastasis by protecting PTEN from oxidation. Shen SM, Guo M, Xiong Z, Yu Y, Zhao XY, Zhang FF, Chen GQ. EMBO reports. 2015;16:1563-80. PubMed: 26415504 PMC: PMC4641507