Human Apolipoprotein H Antibody (IgG) ELISA Kit (Sandwich ELISA)
Catalog Number: LS-F67372-1
1 plate / $591.00
Reactivity: Human
Detection Method Colorimetric
Format: 96-Well Strip Plate
Immunofluorescence analysis of A549 cells, using ADCK4 Antibody. The picture on the right is blocked with the synthesized peptide.
ADCK4 Antibody (aa31-80)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$341.00each
Catalog Number: LS-C119206-50
Catalog Number: LS-C119206
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- ADCK4 antibody LS-C119206 is an unconjugated rabbit polyclonal antibody to ADCK4 (aa31-80) from human. It is reactive with human, mouse and rat. Validated for IF, Peptide-ELISA and WB. Cited in 3 publications.
- Application
- ELISA, IF, IHC, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- ADCK4 | COQ8
- Recommended Dilution: IF/ICC
- 1:100 - 1:500
- Recommended Dilution: WB
- 1:500 - 1:1000
- UniProt Number
- Q96D53
- NCBI GenBank
- AAH13114.2 | NM_024876
- SwissProt
- Q96D53
Target
- Target
- Human ADCK4
- Antigen Species
- Human
- Epitope
- ADCK4 Antibody detects endogenous levels of total ADCK4 protein.
- Gene Name
- COQ8B
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Synthetic peptide from human ADCK4. (AA Range: 31-80)
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
- Volume
- 50 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C for up to 1 year.
- Recommended Storage Buffer
- PBS|150 mM NaCl
Mutations in COQ8B (ADCK4) found in patients with steroid-resistant nephrotic syndrome alter COQ8B function. Vazquez Fonseca L, Doimo M, Calderan C, Desbats MA, Acosta MJ, Cerqua C, Cassina M, Ashraf S, Hildebrandt F, Sartori G, Navas P, Trevisson E, Salviati L. Human mutation. 2018 March;39:406-414.
PubMed: 29194833 · PMC: PMC5838795
ADCK4 Deficiency Destabilizes the Coenzyme Q Complex, Which Is Rescued by 2,4-Dihydroxybenzoic Acid Treatment. Eugen Widmeier, Seyoung Yu, Anish Nag, Youn Wook Chung, Makiko Nakayama, Lucía Fernández-Del-Río, Hannah Hugo, David Schapiro, Florian Buerger, Won-Il Choi, Martin Helmstädter, Jae-Woo Kim, Ji-Hwan Ryu, Min Goo Lee, Catherine F Clarke, Friedhelm Hildebrandt, Heon Yung Gee. Journal of the American Society of Nephrology : JASN. 2020 June;31:1191-1211.
PubMed: 32381600 · PMC: PMC7269352
Identification of a common polymorphism in COQ8B acting as a modifier of thoracic aortic aneurysm severity. Benjamin J Landis, Dongbing Lai, Dong-Chuan Guo, Joel S Corvera, Muhammad T Idrees, Henry W Stadler, Christian Cuevas, Gavin U Needler, Courtney E Vujakovich, Dianna M Milewicz, Robert B Hinton, Stephanie M Ware. HGG advances. 2022 January;3.
PubMed: 34917985 · PMC: PMC8670066
