ABCC2 / MRP2 Antibody (clone M2III-5, Concentrated)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunocytochemistry, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$533.00each
Catalog Number: LS-C134870-1
Catalog Number: LS-C134870
For bulk orders or custom formulations:
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- Description
- MRP2 antibody LS-C134870 is an unconjugated mouse monoclonal antibody to human MRP2 (ABCC2). Validated for Flow, ICC, IHC and WB.
- Application
- FC, ICC, IHC, IHC-F, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- ABC30 | ABCC2 | CMOAT1 | CMOAT | DJS | Multidrug resistance protein 2 | MRP2 | CMRP
- UniProt Number
- Q92887
- NCBI GenBank
- NM_000392 | NP_000383.1
- SwissProt
- Q92887
Target
- Target
- Human ABCC2 / MRP2
- Antigen Species
- Human
- Epitope
- M2III-5 reacts with an internal epitope of MRP2, a 190-200 kD transmembrane protein earlier known as the canalicular multi-organic anion transporter cMOAT, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. MRP2 is a member of the MRP family of multidrug resistance related proteins, and MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. M2III-5 was raised against a fusion protein of the bacterial maltose binding protein and rat Mrp2, containing the 202-amino acid COOH terminal end of the transporter protein. The Mab detects rat, mouse and human MRP2. M2III-5 does not cross-react with the human MDR1 P-gp, MRP1, MRP3 orMRP5 gene products.
- Gene Name
- ABCC2
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- M2III-5
- Isotype
- IgG2b
Immunogen
- Immunogen
- Fusion protein of the bacterial maltose binding protein and rat Mrp2, containing the 202-amino acid COOH terminal end of the transporter protein.
- Immunogen Type
- Fusion Protein (e.g., GST, MBP tag)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- Tissue Culture Supernatant, 0.1% Sodium Azide, 0.7% BSA, Serum-free
- Volume
- 1 Milliliter
- Preservative
- Yes
- Purification Method
- Unpurified (Serum / Ascites / Supernatant)
Storage & Handling
- Storage Conditions
- Store at 2-8°C.