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| Catalog Number | Size | Price |
|---|---|---|
| LS-A1339-50 | 50 µg (1 mg/ml) | $440 |
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2 of 3
3 of 3
PathPlus™ Polyclonal Rabbit anti‑Human TACR1 / NK1R Antibody (Extracellular Domain, IHC) LS‑A1339
PathPlus™ Polyclonal Rabbit anti‑Human TACR1 / NK1R Antibody (Extracellular Domain, IHC) LS‑A1339
Antibody:
TACR1 / NK1R Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bovine, Dog
Format:
Unconjugated, Unmodified
Overview
Antibody:
TACR1 / NK1R Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bovine, Dog
Format:
Unconjugated, Unmodified
Specifications
Description
Tachykinin Receptor 1 (TACR1) is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. TACR1 is associated with the management of depression, anxiety, and stress. It is furtehr involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. In disease, TACR1 is implicated in the progression of rheumatoid arthritis and osteoarthritis.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human TACR1 / NK1R
Synonyms
TACR1 | Neurokinin receptor 1 | NK-1R | Nk1 tachykinin receptor | NK1R | TAC1R | Tachykinin 1 receptor | NKIR | Substance-P receptor | Neurokinin 1 receptor | NK-1 receptor | Tachykinin receptor 1
Host
Rabbit
Reactivity
Human, Monkey, Bovine, Dog
(tested or 100% immunogen sequence identity)
Predicted
Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 2nd extracellular domain of human Neurokinin 1 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bovine, Dog (100%); Rabbit (94%); Elephant, Horse, Guinea pig (88%); Mouse, Rat, Hamster, Opossum (81%).
Epitope
Extracellular Domain
Specificity
Human Neurokinin 1 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (2 - 4 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TACR1 / NK1R
Validation
Brain, Caudate neuron
Brain, Caudate neuron
Anti-Neurokinin 1 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Neurokinin 1 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TACR1 / NK1R antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TACR1 / NK1R antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ TACR1 / NK1R Antibody (Extracellular Domain) for IHC LS-A1339 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin
Species:
Rat, Mouse, Guinea pig
Applications:
IHC, IHC - Frozen
Species:
Human, Monkey, Rat, Guinea pig, Hamster, Horse, Rabbit
Applications:
IHC, IHC - Paraffin
Reactivity:
Mouse
Range:
78.125-5000 pg/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
