Monoclonal Mouse Biotin Antibody
Catalog Number: LS-C127042-200
200 µg / $755.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Format: Liquid
Formalin-fixed, paraffin-embedded Human Testis stained with Wilm's Tumor Mouse Recombinant Monoclonal Antibody (rWT1/857).
Recombinant Monoclonal Mouse anti-Human WT1 / Wilms Tumor 1 Antibody (clone rWT1/857, Azide-free,Carrier-free, IHC)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751421-100
Catalog Number: LS-C751421
For bulk orders or custom formulations:
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- Description
- Wilms Tumor 1 antibody LS-C751421 is an unconjugated mouse recombinant monoclonal antibody to human Wilms Tumor 1 (WT1). Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- GUD | EWS-WT1 | Amino-terminal domain of EWS | WAGR | WIT-2 | Wilms tumor protein | WT1 | AWT1 | Wilms tumor 1 | WT33 | NPHS4 | WT-1
- Recommended Dilution: IHC-P
- 1 - 2 µg/ml
- UniProt Number
- P19544
- NCBI GenBank
- NM_024426 | NP_077744.3
- SwissProt
- P19544
Target
- Target
- Human WT1 / Wilms Tumor 1
- Antigen Species
- Human
- Epitope
- Recognizes a 47-55 kDa -tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm's tumors. WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilm's tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilm's tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
- Gene Name
- WT1
Antibody
- Host Species
- Mouse
- Clonality
- Recombinant Monoclonal
- Clone
- rWT1/857
- Isotype
- IgG1
- Light Chain
- Kappa Light Chain
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human WT1 protein. Antigen Molecular Weight: 47-55 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 1 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 1 mM PBS