Monoclonal Mouse Biotin Antibody
Catalog Number: LS-C127042-200
200 µg / $755.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Format: Liquid
Formalin-fixed, paraffin-embedded Melanoma stained with Tyrosinase Rabbit Recombinant Monoclonal Antibody (TYR/2024R).
Recombinant Monoclonal Rabbit anti-Human Tyrosinase Antibody (clone TYR/2024R, Azide-free,Carrier-free, IHC)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751406-100
Catalog Number: LS-C751406
For bulk orders or custom formulations:
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- Description
- Tyrosinase antibody LS-C751406 is an unconjugated rabbit recombinant monoclonal antibody to human Tyrosinase. Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- CMM8 | LB24-AB | SHEP3 | SK29-AB | Monophenol monooxygenase | Tumor rejection antigen AB | TYR | OCA1A | Tyrosinase | OCAIA
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P14679
- NCBI GenBank
- NM_000372 | NP_000363.1
- SwissProt
- P14679
Target
- Target
- Human Tyrosinase
- Antigen Species
- Human
- Epitope
- Recognizes a cluster of proteins between 70-80 kDa , identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.
- Gene Name
- TYR
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- TYR/2024R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human tyrosinase (TYR) protein. Antigen Molecular Weight: 70-80 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS