TP53 / p53 Antibody (aa20-25, clone DO-1, Biotin)

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Antibody:	Mouse Monoclonal
Applications:	Immunohistochemistry, Paraffin
Reactivity:	Human
Format:	Liquid

$350.00each

Catalog Number: LS-C43827-0.1

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Description: P53 antibody LS-C43827 is a biotin-conjugated mouse monoclonal antibody to human p53 (TP53) (aa20-25). Validated for IHC.
Application: IHC-P
Reactivity: Hu
Nonreactive Species: Ms, Rt
Intended Use: RUO
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: BCC7 | Cellular tumor antigen p53 | p53 | TRP53 | TP53 | p53 tumor suppressor | Phosphoprotein p53 | Antigen NY-CO-13 | Tumor protein p53 | Tumor suppressor p53 | LFS1
UniProt Number: P04637
NCBI GenBank: NM_000546, NP_000537.3
SwissProt: P04637

Target: Human TP53 / p53
Antigen Species: Hu
Epitope: Recognizes the human p53 tumor suppressor protein, also known as cellular tumor antigen p53 or NY-CO-13. Clone DO-1 binds to both wild type and mutant forms of the p53 protein found in various malignancies. p53 is important in multicellular organisms, where it regulates cell cycle progression to allow DNA repair or apoptosis in the case of irreparably damaged cells and thus functions as a tumor suppressor that is involved in preventing cancer. Mutations in the p53 gene are found in about half the cases of human cancerrecognizes an epitope at the N-terminal end of p53 between amino acids 20-25, common to isoforms 1-3 of p53.
Gene Name: TP53

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS

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