LSBio
TOLLIP Antibody

Immunohistochemistry of paraffin-embedded human glioma cancer using TOLLIP Antibody at dilution of 1:100

TOLLIP Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all Human TOLLIP antibodies →
$300.00each
Catalog Number: LS-C501870-50

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Overview

Description
TOLLIP antibody LS-C501870 is an unconjugated rabbit polyclonal antibody to human TOLLIP. Validated for ELISA and IHC.
Application
ELISA, IHC
Reactivity
Hu
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Adapter protein | IL-1RAcPIP | Toll interacting protein | Toll-interacting protein | TOLLIP
UniProt Number
Q9H0E2
SwissProt
Q9H0E2

Target

Target
Human TOLLIP
Antigen Species
Hu
Epitope
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
Gene Name
TOLLIP

Antibody

Host Species
Rb
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Toll-interacting protein (86-163AA)
Immunogen Type
Recom

Format

Conjugate/Label
Unconj
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Prot G

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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