RB1 / Retinoblastoma / RB Antibody (clone 1F8, HRP)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Immunohistochemistry, Frozen, Immunoprecipitation, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$647.00each
Catalog Number: LS-C827953-0.05
Catalog Number: LS-C827953
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- Description
- RB antibody LS-C827953 is an HRP-conjugated mouse monoclonal antibody to RB (RB1 / Retinoblastoma) from human. It is reactive with human and mouse. Validated for IHC, IP and WB.
- Application
- IHC-F, IP, WB
- Reactivity
- Hu, Ms
- Intended Use
- RUO
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- p105-Rb | Osteosarcoma | PRb | RB1 | Retinoblastoma | Retinoblastoma 1 | OSRC | RB | Pp110
- UniProt Number
- P06400
- NCBI GenBank
- NM_000321, NP_000312.2
- SwissProt
- P06400
Target
- Target
- Human RB1 / Retinoblastoma / RB
- Antigen Species
- Hu
- Epitope
- This antibody recognizes retinoblastoma-associated protein (RB), a 105kDa tumor suppressor which is also known as Rb1. Rb1 functions as a transcription factor that controls cell cycle progression (at the G1/S phase transition) through its repression of E2F-mediated transcription. Mutation of the Rb gene is found frequently in human sarcomas, lung, bladder and breast carcinomas and is the molecular basis for hereditary disposition to retinoblastoma.
- Gene Name
- RB1
Antibody
- Host Species
- Ms
- Clonality
- Monoclonal
- Clone
- 1F8
- Isotype
- IgG1
- Origin Species
- Hu
Immunogen
- Immunogen
- Rb-b-galactosidase fusion protein spanning nucleotides 1126-1973 of human Rb gel purified from bacterial lysates
- Immunogen Type
- Fusion-P
Format
- Conjugate/Label
- HRP
- Format
- Liquid
- Formulation
- PBS, 0.01% Thiomersal
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Prot A
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS