Formalin-fixed, paraffin-embedded human Parathyroid stained with PTH Rabbit Recombinant Monoclonal Antibody (PTH/2295R).
PTH / Parathyroid Hormone Antibody (clone PTH/2295R, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751327-100
Catalog Number: LS-C751327
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- Description
- Parathyroid Hormone antibody LS-C751327 is an unconjugated rabbit recombinant monoclonal antibody to human Parathyroid Hormone (PTH). Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- Parathyroid hormone | Parathyroid hormone 1 | PTH | Parathyrin | Parathormone | PTH1
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P01270
- NCBI GenBank
- NM_000315 | NP_000306.1
- SwissProt
- P01270
Target
- Target
- Human PTH / Parathyroid Hormone
- Antigen Species
- Human
- Epitope
- Epitope of this MAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH) - also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
- Gene Name
- PTH
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- PTH/2295R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide corresponding to amino acids 1 to 34 of mature PTH conjugated to a carrier. Antigen Molecular Weight: 9 kDa
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS