PHA-stimulated (day-3) human peripheral blood lymphocytes stained with purified EH12.2H7, followed by anti-mouse IgG FITC
PDCD1 / CD279 / PD-1 Antibody (clone EH12.2H7)
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry (general) |
| Reactivity: | Human |
| Format: | Liquid |
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- Description
- PD-1 antibody LS-C40800 is an unconjugated mouse monoclonal antibody to human PD-1 (PDCD1 / CD279). Validated for Flow. Cited in 7 publications.
- Application
- FC, IHC
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD279 | HPD-1 | HPD-l | PD1 | PDCD1 | Protein PD-1 | SLEB2 | PD-1 | CD279 antigen | Programmed cell death 1
- UniProt Number
- Q15116
- NCBI GenBank
- NM_005018 | NP_005009.2
- SwissProt
- Q15116
Target
- Target
- Human PDCD1 / CD279 / PD-1
- Antigen Species
- Human
- Gene Name
- PDCD1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- EH12.2H7
- Isotype
- IgG1
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.2, 0.09% Sodium Azide
- Concentration
- 0.5 mg/mL
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at 4°C. Store undiluted.
- Recommended Storage Buffer
- PBS
Simian immunodeficiency virus (SIV)-specific CD8+ T-cell responses in vervet African green monkeys chronically infected with SIVagm. Zahn RC, Rett MD, Korioth-Schmitz B, Sun Y, Buzby AP, Goldstein S, Brown CR, Byrum RA, Freeman GJ, Letvin NL, Hirsch VM, Schmitz JE. Journal of virology. 2008;82:11577-88.
PubMed: 18829748 · PMC: PMC2583661
Cutting edge: Programmed death-1/programmed death ligand 1 interaction regulates the induction and maintenance of invariant NKT cell anergy. Chang WS, Kim JY, Kim YJ, Kim YS, Lee JM, Azuma M, Yagita H, Kang CY. Journal of immunology (Baltimore, Md. : 1950). 2008;181:6707-10.
PubMed: 18981087
Human immunodeficiency virus type 1 escapes from interleukin-2-producing CD4+ T-cell responses without high-frequency fixation of mutations. Jones RB, Yue FY, Gu XX, Hunter DV, Mujib S, Gyenes G, Mason RD, Mohamed R, MacDonald KS, Kovacs C, Ostrowski MA. Journal of virology. 2009;83:8722-32.
PubMed: 19553327 · PMC: PMC2738181
Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic. Vojnov L, Reed JS, Weisgrau KL, Rakasz EG, Loffredo JT, Piaskowski SM, Sacha JB, Kolar HL, Wilson NA, Johnson RP, Watkins DI. Journal of virology. 2010;84:753-64.
PubMed: 19889785 · PMC: PMC2798340
Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling. Radziewicz H, Ibegbu CC, Hon H, Bdard N, Bruneau J, Workowski KA, Knechtle SJ, Kirk AD, Larsen CP, Shoukry NH, Grakoui A. Journal of immunology (Baltimore, Md. : 1950). 2010;184:2410-22.
PubMed: 20100932 · PMC: PMC2924663
Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin 7. Monteiro P, Gosselin A, Wacleche VS, El-Far M, Said EA, Kared H, Grandvaux N, Boulassel MR, Routy JP, Ancuta P. Journal of immunology (Baltimore, Md. : 1950). 2011;186:4618-30.
PubMed: 21398606
Dominant clonotypes within HIV-specific T cell responses are programmed death-1high and CD127low and display reduced variant cross-reactivity. Conrad JA, Ramalingam RK, Smith RM, Barnett L, Lorey SL, Wei J, Simons BC, Sadagopal S, Meyer-Olson D, Kalams SA. Journal of immunology (Baltimore, Md. : 1950). 2011;186:6871-85.
PubMed: 21562156 · PMC: PMC3403726