Human NGFR / CD271 / TNR16

Rabbit

Human, Mouse (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated. Also available conjugated with Biotin, HRP, FITC.

Protein G purified

Unmodified

Recombinant Human Tumor necrosis factor receptor superfamily member 16 protein (277-391AA)

Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

• IHC
• Western blot
• ELISA

PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.

Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P08138 NCBI: NM_002507 NP_002498.1