Formalin-fixed, paraffin-embedded human Melanoma stained with NGFR Rabbit Recombinant Monoclonal Antibody (NGFR/2550R).
NGFR / CD271 / TNR16 Antibody (aa 281-421, clone NGFR/2550R)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751299-20
Catalog Number: LS-C751299
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- Description
- TNR16 antibody LS-C751299 is an unconjugated rabbit recombinant monoclonal antibody to human TNR16 (NGFR / CD271) (aa 281-421). Validated for IHC.
- Application
- IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- CD271 | CD271 antigen | gp80-LNGFR | Nerve growth factor receptor | p75 ICD | p75(NTR) | p75NTR | TNFR superfamily, member 16 | NGF receptor | NGFR | TNFRSF16 | p75-NTR
- Recommended Dilution: IHC-P
- 1 - 2 µg/ml
- UniProt Number
- P08138
- NCBI GenBank
- NM_002507 | NP_002498.1
- SwissProt
- P08138
Target
- Target
- Human NGFR / CD271 / TNR16
- Antigen Species
- Human
- Epitope
- It recognizes a glycoprotein of 75 kDa , identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
- Gene Name
- NGFR
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- NGFR/2550R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant human p75 NGFR protein fragment (around aa 281-421). Antigen Molecular Weight: 75 kDa
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS