Positive WB detected in:SH-SY5Y whole cell lysate;All lanes: METTL14 antibody at 3ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 53 kDa;Observed band size: 53 kDa;

METTL14 Antibody

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C502001-50

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Overview

Description: METTL14 antibody LS-C502001 is an unconjugated rabbit polyclonal antibody to human METTL14. Validated for ELISA, IHC and WB.
Application: ELISA, IHC, WB
Reactivity: Hu
Intended Use: RUO
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: KIAA1627 | Methyltransferase like 14 | METTL14
UniProt Number: Q9HCE5
SwissProt: Q9HCE5

Target

Target: Human METTL14
Antigen Species: Hu
Epitope: N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability (PubMed:24316715, PubMed:24407421, PubMed:25719671). M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop. M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization (By similarity).
Gene Name: METTL14