LSBio
MEIKIN Antibody

Immunohistochemistry of paraffin-embedded human placental tissue using MEIKIN Antibody at dilution of 1:100

MEIKIN Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all Human MEIKIN antibodies →
$300.00each
Catalog Number: LS-C500396-50

For bulk orders or custom formulations:

Request a Quote

Overview

Description
MEIKIN antibody LS-C500396 is an unconjugated rabbit polyclonal antibody to human MEIKIN. Validated for ELISA and IHC.
Application
ELISA, IHC
Reactivity
Hu
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies

Target

Target
Human MEIKIN
Antigen Species
Hu
Epitope
Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage. Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis.

Antibody

Host Species
Rb
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant human Meiosis-specific kinetochore protein (18-91AA)
Immunogen Type
Recom

Format

Conjugate/Label
Unconj
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Prot G

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.