
Formalin-fixed, paraffin-embedded human Tonsil stained with MUC18 Mouse Recombinant Monoclonal Antibody (rMUC18/1130).
MCAM / CD146 Antibody (clone rMUC18/1130)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Recombinant Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751264-20
Catalog Number: LS-C751264
For bulk orders or custom formulations:
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- Description
- CD146 antibody LS-C751264 is an unconjugated mouse recombinant monoclonal antibody to human CD146 (MCAM). Validated for IHC.
- Application
- IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- CD146 | CD146 antigen | Gicerin | Melanoma adhesion molecule | MCAM | MUC18 | p1h12
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P43121
- NCBI GenBank
- NM_006500 | NP_006491.2
- SwissProt
- P43121
Target
- Target
- Human MCAM / CD146
- Antigen Species
- Human
- Epitope
- Mel-CAM belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
- Gene Name
- MCAM
Antibody
- Host Species
- Mouse
- Clonality
- Recombinant Monoclonal
- Clone
- rMUC18/1130
- Isotype
- IgG1
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human MUC18 protein. Antigen Molecular Weight: 130 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS
