Formalin-fixed, paraffin-embedded human Pancreas stained with Insulin Mouse Recombinant Monoclonal Antibody (rIRDN/805).

Insulin Antibody (clone rIRDN/805, Azide-free, Carrier-free)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Recombinant Monoclonal
Applications:	Immunohistochemistry, Paraffin
Reactivity:	Human
Format:	Liquid

$586.00each

Catalog Number: LS-C751216-100

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Overview

Description: Insulin antibody LS-C751216 is an unconjugated mouse recombinant monoclonal antibody to human Insulin. Validated for IHC.
Application: IHC-P
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: INS | IRDN | IDDM2 | Preproinsulin | ILPR | Insulin | MODY10 | Proinsulin
Recommended Dilution: IHC-P: 0.5 - 1 µg/ml
UniProt Number: P01308
NCBI GenBank: NM_000207 | NP_000198.1
SwissProt: P01308

Target

Target: Human Insulin
Antigen Species: Human
Epitope: Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Gene Name: INS